Impurities

Ramipril Impurities

  • Ramipril EP Impurity A

  • Impurity: Ramipril EP Impurity A
  • Chemical Name: (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-(methoxycarbonyl)-3-phenylpropyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (ramipril methyl ester)
  • Ramipril -EP Impurity B

  • Impurity: Ramipril -EP Impurity B
  • Chemical Name: (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-[(1-methylethoxy)carbonyl]-3-phenylpropyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (ramiprilisopropyl ester)
  • Ramipril EP Impurity C

  • Impurity: Ramipril EP Impurity C
  • Chemical Name: (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-3-cyclohexyl-1-(ethoxycarbonyl)-propyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (hexahydroramipril)
  • Ramipril EP Impurity D

  • Impurity: Ramipril EP Impurity D
  • Chemical Name: ethyl (2S)-2-[(3S,5aS,8aS,9aS)-3-methyl-1,4-dioxodecahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl]-4-phenylbutanoate (ramipril diketopiperazine)
  • Ramipril EP Impurity E

  • Impurity: Ramipril EP Impurity E
  • Chemical Name: (2S,3aS,6aS)-1-[(2S)-2-[[(1S)-1-carboxy-3phenylpropyl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (ramipril diacid)
  • Ramipril EP Impurity F

  • Impurity: Ramipril EP Impurity F
  • Chemical Name: (2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]propanoic acid
  • Ramipril EP Impurity G

  • Impurity: Ramipril EP Impurity G
  • Chemical Name: methylbenzene
  • Ramipril EP Impurity N

  • Impurity: Ramipril EP Impurity N
  • Chemical Name: (2R,3aR,6aR)-1-[(2S)2[[(1S)1(ethoxycarbonyl)-3-phenylpropyl]amino]propanoyl] octahydrocyclopenta[b]pyrrole-2-carboxylic acid ((S,S,R,R,R)-isomer of ramipril)
  • Ramipril EP Impurity O

  • Impurity: Ramipril EP Impurity O
  • Chemical Name: diethyl 2,2’-(2,5-dimethyl-3,6-dioxopiperazine-1,4-diyl)bis(4-phenylbutanoate)
  • Ramipril Impurity

  • Impurity: Ramipril Impurity
  • Chemical Name: Benzyl(cis,endo)-octahydrocyclopenta[b]pyrrole-2(S)-carboxylate hydrochloride
  • Ramipril Impurity

  • Impurity: Ramipril Impurity
  • Chemical Name: N-[1(S)-Carboethoxy-3-phenylpropyl]-(S)-alanine

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